18 November 2017

Novo Nordisk Symposium

After hosting a successful inaugural symposium in 2016, Hanne Poulsen (Aarhus) and Stephan had been lucky enough to receive a Novo Nordisk Symposium grant to host a number of world-class speakers on the topic of “Studying and controlling membrane proteins with light”: Anna Moroni (Milan, Italy), Peter Hegemann (Berlin, Germany), Ofer Yizhar (Weizmann, Israel), Ehud Isacoff (Berkeley, USA), Baron Chanda (Wisconsin, USA), Antoine Triller (Paris, France), Yuki Bando (Columbia, USA) and Justin Taraska (NIH, USA). We are very grateful to NNF, the speakers and all attendees for making it a great day – and hope to organise a follow up in 2018!

6 November 2017

Welcome Lise

We´re very happy to welcome Lise to the team. Originally from Randers, Denmark, she is an expert in membrane proteins and will join us as a PhD student from December on an exciting new project.

2 November 2017

Funding news

We are very grateful to the Lundbeck Foundation for a running cost grant for a new project in the lab – we are looking forward to putting the grant to good use

30 October 2017

Welcome back, Mette

We are delighted to announce the return of Mette after her maternity leave – welcome back!

23 October 2017

New paper in PNAS

Thanks to the heroic efforts of Drs Kim & Kurata in Edmonton, this nice piece of work illustrates how the voltage-sensing apparatus of neuronal potassium channels is affected by an anti-epileptic drug and the membrane lipid PIP2. Click this LINK for details.

8 October 2017

New paper out

Congrats to Tim, Jose and Camilla for getting their work on ibuprofen and ASICs published in J Med Chem. They investigated the ibuprofen/ASIC interaction by deciphering the mechanism of inhibition, identifying the ibuprofen binding site and using a series of ibuprofen analogs to performing structure-activity-relationships. The KU press release can be found HERE, whereas the full paper can be accessed HERE.

3 October 2017

We´re looking for a postdoc

We are looking to fill a 1-year postdoctoral position in peptide chemistry from 1.1.2018. The project will focus on using solid-phase peptide synthesis (SPPS) and native chemical ligation (NCL) for protein engineering of membrane proteins. Please apply useing the following LINK (note that direct applications via email CAN NOT be accepted).

18 September 2017

Welcome Daniel

Daniel joins us from Germany for an internship until March 2018 to work on peptides interacting with ASICs – welcome and we look forward to having you around!

31 August 2017

Lab retreat 2017

This year, we headed for Bornholm for our annual lab retreat. We got treated to great weather, very pretty landscapes and a seriously wet coastal adventure trip – thanks to everyone for making it a great outing!

26 August 2017

Congrats to Christian and Matthias

Congrats to both Matthias and Christian for taking first place in the talk and poster competitions at the DRA summer school – very well done, gentlemen!

25 August 2017

Benzon Symposium 2017

Benzon Symposium “New Paradigms of Protein Engineering – Applications in Modern Medicine”: a fantastic line up of speakers made for an exiting week with plenty of highlights, covering various aspects of chemical biology around proteins and peptides. A big thank you to all speakers and attendees for making it a great symposium!

21 August 2017

Novo Nordisk Symposium on Nov 16th

The program covers various topics related to how membrane proteins can be studied and controlled using light, from single molecule techniques to systems and optogenetics approaches. We have been able to attract top speakers from around the globe, incl Y. Bando (Columbia University), B. Chanda (University of Wisconsin), A. Cohen (Harvard), P. Hegemann (Berlin), E. Isacoff (Berkeley), A. Moroni (Milan), J. Taraska (NIH) and A. Triller (Paris). Attendance is free of charge, but registration is required by Nov 5th. Please use this LINK to register.

15 August 2017

Congrats to Federica and Daniel

Congrats to both Federica and Daniel for successfully submitting a PhD thesis (Federica) and defending a MSc thesis (Daniel).

Federica deserves a lot of credit for being the first PhD student from the Pless lab to submit a thesis, in which she not only served as teh guiney pig on numerous occasions, but also made great progress towards our understanding of how ATP binds to P2X receptors. After a well-deserved break, Federica will re-join us for a 3-month stay in the fall.

Daniel made some nice progress on the details of ligand binding to a worm GluCl and we wish him all the best for his future – it was great having you around!

4 August 2017

Farewell to Caroline

After a very productive and successful Erasmus internship with us, Caroline is heading back to Germany to start her MSc thesis in Halle. Thanks for your hard work and all the best!

20 July 2017

Congrats to Camilla

Congrats to Camilla for securing a Mobility Scholarship. The money will support her stay abroad at the University of Alberta (Edmonton, Canada), where she will work with Prof. Harley Kurata in early 2018.

9 July 2017

JBC article highlighted

Congrats to Tim (and Vitaly) for having their recent JBC article highlighted in a special (virtual) issue: http://www.jbc.org/site/vi/ionchannels/

7 July 2017

Harbour tour 2017

IMG_5044 IMG_5048After a last minute date change, we managed to catch some sun while cruising through harbour and canals. Thanks to everyone involved for making it a fun outing!

31 May 2017

Congrats and farewell to Sarah

Congrats to Sarah for successfully defending her MSc thesis today. Sarah implemented an assay to optically follow incorporation of unnatural amino acids in mammalian cells, which will no doubt come in very handy in the future. We wish Sarah all the best for her future.

25 May 2017

Breaking down the nerdy stuff

In case the full version is too nerdy for your taste, you can access a more digestible version of Tim´s paper here – LINK.

24 May 2017

Center for Biopharmaceuticals spring picnic

IMG_9392_m IMG_9436_mWe were lucky to catch the warmest day of 2017 yet for our canoe outing to the waters of beautiful Furesø. Lots of fun and game made for a great day – thanks a lot to the organisiers for making it happen.

 

12 May 2017

Tim´s paper accepted in eLife

IMG_2618Congrats to Tim, our collaborators in Melbourne (Toby, Emelie and Celine), as well as everyone else involved at our end (Matthias, Vitaly and Janne) for finishing this study! Using a variety of approaches, we believe we have found the selectivity filter of acid-sensing ion channels – check out the details here.

24 April 2017

Welcome Zeshan

Today, we welcome our latest PhD student, Zeshan Sheikh – a local with extensive expertise in membrane protein biochemistry. Looking forward to having you on the team!

24 April 2017

Facebook feature

Check out the Facebook page of Lundbeckfonden to see a video featuring Christian´s project on spider toxins and ASIC channels.

9 April 2017

Open PhD position

We are starting to work on a new, exciting protein and are looking for a highly-motivated PhD student to join our team from October: http://employment.ku.dk/phd/?show=901427

 

5 April 2017

Congrats to Nina

Nina receives a travel grant from the Physiological Society to attend the FEBS/EMBO lecture course on “Ion Channels and Transporters” in Erice – congrats and enjoy Italy!

28 March 2017

Congrats to Christian!

Congrats to Christian for securing a travel grant from the Lundbeck Foundation to attend the Biophysical Society meeting in New Orleans – well done!

20 March 2017

Welcome Caroline

Coming from Halle, Germany, Caroline will join us as an Erasmus student over the summer. Welcome and we´re looking forward to having you around.

19 February 2017

Tim talks

IMG_3376After Tim and Stephan already visited Boston and Austin (where they came across some flying canoes…), they met up with Federica, Christian and Matthias to attend the 2017 Biophysics meeting in New Orleans. Congrats to Tim for being selected to give a talk at the  meeting on his latest work on ASICs! Well done also by Federica, Christian and Matthias for attracting lots of attention with their posters.

8 February 2017

Congrats to Federica

Federica continues her successful streak at applying for travel support, this time in form of a travel grant from Oticon to attend the Biophysics meeting in New Orleans – congrats!

1 February 2017

Hi and goodbye

While we´re sad to say goodbye to Britt, our first lab technician intern ever, we´re very excited to welcome her successor, Natasha, to the team – glad to have you around!

We wish Britt all the best for her future and will certainly miss her smile (and help!) around here.

18 January 2017

Center for Biopharmaceuticals annual retreat

IMG_8935_very smallAs is now tradition within the Center for Biopharmaceuticals, the whole crew took to Snekkersten in January – this time with a record-breaking 43 participants. Entertained by excellent speakers, we learned a lot about “Publishing and outreach”, this years topic for the retreat. Thanks to everyone for making this a memorable outing – in particular to Ulla for taking care of a very smooth organisation.

17 January 2017

New paper in JBC

Tim and Vitaly got the lab off to a flying start in 2017 – congrats for having their paper entitled “Unique contributions of an arginine side chain to ligand recognition in a glutamate-gated chloride channel” accpeted at the Journal of Biological Chemistry! A nice example of how unnatural amino acids can be used to introduce a titratable arginine analog into an ion channel – and uncovering a surprising side chain contribution to ligand recognition. A free PDF of the article can be found by clicking this LINK.

1 January 2017

Open PhD position

If you have a MSc degree and practical experience in the use of electrophysiology, unnatural amino acids and molecular biology, please follow this LINK to submit your application. Please note that direct applications via email can not be considered.

29 November 2016

Fluorescence Symposium

speakers-small

audience-small We were fortunate enough to attract an amazing line up of speakers for a symposium focused on fluorescence-based approaches to study membrane proteins. Together with Hanne Poulsen (Aarhus), this meant bringing Teresa Giraldez (La Laguna, Spain), Chris Ahern (Iowa, US), Pancho Bezanilla (Chicago, US), Kevin Eggan (Harvard, US), Poul Nissen (Aarhus), Dimitrios Stamou (KU), Dirk Trauner (Munich, Germany) and Bill Zagotta (Washington, US) to Copenhagen. A huge thank you to our sponsors for financial suport, Ulla Jakobsen for invaluable help with the organisation and all speakers for making this a great day! Keep your eyes peeled for the 2017 edition of this event, which will feature a number of world-class speakers as part of a Novo Nordisk Foundation Symposium on Nov 16th 2017- details to follow in the spring.

26 November 2016

Success at Carlsberg

Stephan was fortunate enough to be awarded a Carlsberg Foundation ‘Distinguished Associate Professor Fellowship’, which we will put to good use on a new project over the next three years!

19 November 2016

Congrats to Nina. Again.

Competing with other PhD students from all over Europe, Nina was able to secure a coveted Boehringer Ingelheim Fond PhD fellowship – congrats and well done, Nina!

11 November 2016

Noise

img_2620You would think that 2 years after moving in we would be past any issues related to noise. Well, think again. Thanks to a (not so) brilliantly timed and communicated renovation effort half the department will need to come to work with heavy-duty ear mufflers until the end of the year – or just stay at home. Then again, at least we´ll be well prepared to deal with the inevitable Christmas jingle onslaught.

27 October 2016

Congrats to Nina

We´re very happy to report that Nina just received a PhD scholarship from the Lundbeck Foundation!

15 September 2016

Welcome Camilla, Daniel and Sarah

After some of them had already joined us on our lab retreat, we´re very happy to have three new MSc students join the team: Camilla Lund, Daniel Vasquez and Sarah Yandurah – looking forward to having you guys around!

5 September 2016

Lab retreat 2016

IMG_2047Amidst picture perfect weather and the beautiful landscape of Kullen, we spent a couple of days on very productive science sessions and some fun outdoor adventures. Thanks to everyone for making this a memorable trip – and respect for daring to take on all the outdoor fun!

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5 September 2016

Say hi to Mette

A Copenhagen native, Mette is an ion channel expert joining us for a postdoc after a very successful stay in Andrew Plested´s lab in Berlin. Welcome, great to have you around!

2 September 2016

DHL run

20160902_180217-REVAs per usual, the members of the Center for Biopharmaceuticals were keen contributors at the annual DHL race – congrats to everyone involved and thanks for making it a fun event!

27 August 2016

Congrats to Jose

jose 2After working on his MSc thesis under the supervision of Tim since 2015, Jose sucessfully submitted and defended his thesis last week – congrats on a great job, Senor Romero! Jose will be finishing off the project with us over the next couple of weeks, after which we will submit the work of him and Tim – stay tuned for a neat piece of molecular pharmacology!

15 August 2016

Welcome Chow

Chow is an ion channel expert joining from the University of Sydney, Australia, who will be working on a new project in the lab. Welcome, looking forward to having you around!

31 July 2016

Tim talks

Tim was invited to give a talk at the “Novel approaches to probe the molecular function of ion channels from the nicotinic superfamily” symposium at the Physiological Society Meeting in Dublin – see link here.

25 July 2016

Congrats to Federica. Again.

Thanks to fellowships from the Lundbeck Foundation and the organising committee, Federica gets to attend the Genetic Code Expansion workshop and conference in August in Oregon. Check out the meeting details here.

12 July 2016

Congrats. To Tim. Again.

Tim gets voted next Ion Channel GRS chair by his peers! Congrats and we look forward to a great GRS program in 2018 then!

10 July 2016

Congrats to Tim

Tim had the honor of being seletced for a talk at the Ion Channel GRS in South Hadley, MA – congrats!

8 July 2016

Farewell Jianmin

IMG_1270 copy_smalllAfter just under 3 months in Copenhagen, visiting Professor Jianmin Cui is heading back to St Louis – he will be missed, it was fantastic having such a great scientist around!

30 June 2016

Farewell Alba and Vaida

We´d like to say thanks to both Alba and Vaida for all their help and contributions in the lab and we wish them all the best for their future!

16 June 2016

Congrats to Jianmin

Jianmin receives a “Visiting Professor” grant from the Lundbeck Foundation in relation to his stay with us over the summer – congrats!

16 June 2016

It´s a tradition

IMG_0893_smallDespite the unpredicabtle weather conditions, we were lucky enough to catch some sun during our annual boat outing. While testing the nerves of some of the tour boat operators, we managed to successfully navigate through various canals and managed to safely return to shore – we´ll be back in 2017!

15 June 2016

Welcome Keith

We welcome Keith to the lab, who will be joining us for a 2-year postdoc. Originally from Singapore, Keith joins us from Melbourne, where he has been very productive working on all sorts of ion channel and peptide-related projects – looking forward to having you around!

9 June 2016

Novo Nordisk Foundation Symposium Grant

Together with Hanne Poulsen (Aarhus), Stephan was granted a Novo Nordisk Foundation Symposium Grant on “New paradigms in fluorescence-based approaches to study membrane proteins” in 2017 – more details to follow later in the year, but rest assured we will do everything we can to put together an exiting program!

6 June 2016

Welcome Anna

Anna will be joining us over the summer from Darmstadt, Germany, to do some electrophysiology  – welcome, and we look forward to having you around!

19 May 2016

Welcome Vaida

Vaida, who just finished her PhD at KU, is an expert in worm genetics and will learn some ephys while in our lab over the summer. Welcome, and we look forward to learning more about worms and genetics from you!

25 April 2016

Welcome Prof Jianmin Cui

It is our great plasure to host Prof Jianmin Cui, Spencer T. Olin Professor of Biomedical Engineering at Washington University in St. Louis over the summer in our laboratory. Jianmin is an expert in ion channel biophysics and we very much look forward to having him (and his expertise) around for the next couple of months!

19 April 2016

Talk in Frankfurt

FRAThanks to an invitation by the ‘Membrane Transport’ consortium at the MPI/University in Frankfurt, Stephan had the pleasure to meet with and talk to members of one of the German strongholds in membrane protein structure and function research – a big thank you to the hosts Misha, Inga, Robert and Marina for a terrific visit!

20 March 2016

Welcome Lea

This week, we have the pleasure of introducing Lea Sørensen to our team – Lea will be helping us as a Research Assistant until the summer. Welcome on board!

4 March 2016

Biophysical Society meeting 2016

Courtesy to travel awards to Federica (Biochemical Society), Matthias (Lundbeck) and Tim (DFF), we were able to treck across the pond with quite a few lab members this year. Greeted by sunny and warm weather, it quickly became clear that – thanks to a busy program – we would not have time to indulge in either. Instead, we were treated to an excellent meeting, with very successful poster presentations by Nina, Federica and Matthias.

15 February 2016

Welcome Nina and Alba

After a very productive MSc thesis last year, Nina returns as a PhD student this week. Alba joins us from Spain for an internship over the summer. Welcome both, we´re very much looking forward to having you around!

12 February 2016

Welcome Britt

We´re very happy to be joined by Britt, who will stay with us for the coming year as a laboratory technician intern. Hailing from New Orleans, Britt is the latest addition to the team and will help us cope with the growing demand in help with molecular biology. Welcome to the crew!

12 February 2016

Federica is back

After 3 months in Strasbourg, Federica returns with plenty of single channel data – and awards from Oticon, A.P.Møller, Augustinus, Knud Højgaards and Christian og Ottilia Fonden, supporting her work over there. Congrats on a very productive and successful trip!

 

6 February 2016

Ligand Recognition and Molec. Gating GRC

IMG_5203This years edition of the Ligand Recognition & Molecular Gating GRC took place in Tuscany and featured a spectacular line up of speakers. Despite the mostly gloomy weather, the meeting was very inspiring and extremely informative for anyone into molecular aspects of membrane protein structure and function – big props to the organisers for putting together a great program!

31 January 2016

We´re looking for postdocs!

Interested in working with us a postdoc? If you have an exceptionally strong background in electrophysiology or would like to apply your chemical biology expertise to ion channels, apply here.

18 January 2016

New paper for the lab

Together with our colleagues in Oxford, we just published a manuscript in ACS Chemical Neuroscience on the role of an absolutely conserved pair of tryptophan side chains in Cys-loop receptors – congrats to all involved, in particular Nina and Tim! Find the link here.

Graphical TOC

12 January 2016

Welcome Christian. Again.

After his brief stint as a Research Assistant, we are extremely happy to welcome Christian as our new PhD student. The Copenhagen local is an expert biochemist with plenty of experience with proteins – and thus a perfect match for our team. Welcome, Christian!

8 December 2015

Symposium on novel approaches in ion channel research

We recently had the pleasure to host a DRA & Center for Biopharmaceuticals minisymposium entitled “Thinking outside the box – Novel approaches to study ion channels”. The event included lectures by Prof. Chris Ulens (Leuven, Belgium), Dr. Thomas Berger (Bonn, Germany) and Prof. Friedrich Koch-Nolte (Hamburg, Germany) and covered a wide array of novel approaches to study ion channels, incl. fluorometry, crystallography, fragment-based screening and nanobodies. The event provided a beautiful showcase of how implementation of recent technical advances can lead to exciting new findings, both with regards to functional and pharmacological studies on ion channels.

IMG_8154_croppedStephan along with Profs Ulens, Koch-Nolte and Berger (from left)

9 November 2015

Welcome Christian

Christian Bernsen Borg will be joining us as a research assitant, before starting his PhD with us later in the year. Christian is a Copenhagen native and an expert in proteins, thus making for a great addition to our team!

29 October 2015

Goodbye to Vitaly

We´re sad to have to say goodbye to Vitaly – but at the same time we´re very excited to see him leave for such an great job at Novo and wish him all the best for his future!

It really was fantastic to have you around, Vitaly, and we will certainly miss you!

15 October 2015

Lots of familiar faces

With visits from Germany (Gisi Seebohm), the US (Bill Kobertz) and Japan (Takahiro Yasuda) we had a very international set of visitor come to our lab last week – it was fun to see you all guys, and sorry we didn´t have more time!

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15 October 2015

Experts in town

After months of planning, the big day had finally come: Oct 6th, the day of the “Hot topics in protein medicinal chemistry” symposium. The line-up was absolutely world class and I think it´s safe to say nobody in the audience went home disappointed – the lectures were absolutely outstanding and extremely inspirational! More coverage of the event can be found here!

15 October 2015

More travel for Stephan

IMG_4331Stephan had the pleasure to be invited to the annual meeting of both the French and the Spanish ion channel communities – two fantastic showcases of the exciting ion channel work being done in the warm south! Thanks very much to the organisers for arranging great meetings! prbbIII(Photo credit: PRBB, likely the research institute with the best location ever  – in the center of Barcelona, only meters from the beach…)

21 September 2015

It took a while

We´re happy to report the publication of the (likely first) book on how to apply chemical biology approaches to ion channel research – published by Springer, the work can be find under this link. We were very fortunate to be able to recruit world-leading experts to contribute to the book and hope it will find widespread application in the field!

21 September 2015

Thanks for the feature

Our latest work on potassium channels modulators just got featured in a science blog – find the details here

3 September 2015

New publication

Together with our colleagues in Canada, the US and Germany, we have published our latest work in Nature Communications. The work directly shows how a recently marketed anti-epileptic drug elicits its action on a neuronal ion channel. Using synthetic amino acids, we were able to show that the drug, retigabine, binds to the channel primarily via a single hydrogen bond. Curiosly, the H-bond donor within the channel turned out to be the indole nitrogen of a tryptophan side chain, constituting a previously undescribed mechanism of a drug-receptor interaction. Ongoing research in our group, in collaboration with partners from both industry and academia (in Denmark, Canada and Germany), now focuses on complementing this work with detailed SAR studies of retigabine – see also current MSc projects.

31 August 2015

New grants

We were fortunate enough to receive grant support for purchasing new equipment from the Beckett Foundation, Brodrene Hartmann Foundation and the Hørslev Foundation – we are very grateful for their support!

30 August 2015

Goodbye to Nina and Michael

In the past week, we said goodbye to both Nina and Michael, who did an outstanding job in the lab over the last couple of months! While Nina decided to head home the hard way (1200 km by bike), Michael had no choice but to hop on a plane back to the West Coast…

29 August 2015

Congrats to Federica

Federica won the poster competition amongst the 2nd year PhD students at the DRA Summer School 2015 – congrats on a job well done! See the link for details

21 August 2015

The tradition with the boat

boat trip 2015In attempt to establish a lab tradition, we made good use of the (finally) summer-like temperatures and went on a little boat tour around the harbour – great fun, despite the slow speed!

23 July 2015

New paper

Together with our friends in Edmonton and Iowa, we have just had a paper accepted at Nature Communications – congrats to all involved. Details to follow follow soon!

23 July 2015

Talk at UCL

Thanks to Lucia Sivilotti, the leading glycine receptor single channel aficionado (see her recent award lecture on the topic here), Stephan had the pleasure of being invited to UCL for a talk. This meant getting a chance to catch up with some of the world-leading ion channel experts in what has to be the  at one of the strongest ion channel/neuroscience departments around – thanks for a great visit.

19 July 2015

Lab retreat

IMG_4012s

As our inaugural lab retreat, we left Copenhagen to not only discuss the latest science going on in the lab, but also to check out some massive underground features in nearby Hamburg. More precisely, the tunnels of DESY – built to enlighten us science nerds on all sorts of fancy topics, ranging from our X-ray crystallography of biomolecules (which we are known to occasionally deal with) to quarks, gluons, dark matter and quite literally the big bang itself…

IMG_4016s

 

1 July 2015

Open PhD position

We currently have a PhD position available for a highly motivated student – check out the details here.

30 June 2015

A special guest

We had the great pleasure of welcoming Prof Joe Lynch to town this week. One of the leading glycine receptor experts around, he also was responsible for much of the scientific training of Tim and Stephan, who both did their PhDs with him. More info on Joe can be found here.

 

22 June 2015

Sailing, Viking style

IMG_3801Despite the daunting weather forecast, the members of the Center for Biopharmaceuticals took to the sea at Roskilde in a boat replica of what would have been used by the Vikings a long while back – a fun ride that definitely instilled a lot of respect for those who used tiny boats like these to brave the open waters of the North Sea!

 

1 June 2015

Welcome!

Jose will be working on his MSc thesis with us as part of his MSc degree in Human Biology (here at KU), while Michael is an undergraduate student from the University of British Columbia who is visiting us for the summer – welcome on board, gentlemen!

14 May 2015

Thank you, Matthias

IMG_3487sA big thank you to Matthias for taking on the task of putting together our first-ever patch rig – stay tuned for what he is going to use it for!

9 May 2015

Jason Chin in Aarhus

Aarhus tripVitaly and Stephan got on the train to Aarhus to attend a talk by Jason Chin from Cambridge. After a pleasant ride through the beautiful Danish spring, there were treated to an outstanding lecture about the possibilities of using an expanded genetic code to address a wide variety of chemical and biological questions – very inspiring indeed! Learn more about Jason Chin´s work here.

25 April 2015

Finally.

After numerous delays and many disruptions, we are delighted to announce that our lab space is finally completely ready for use! Many thanks to all involved in this process – we are delighted with our new playground!

20 April 2015

Talk at the Gage Conference

IMG_3383_sStephan had the honour of being in invited to give a talk at the Gage Conference in Canberra, Australia. Although this meant spending an awful lot of time on airplanes, it was definitely worth every minute, given the very fruitful interactions with collaborators and friends – on top of the many exciting talks at the meeting. A big thank you to Brett, for making this trip possible!

17 March 2015

Vitaly joins the lab

Vitaly Komnatnyy joins the lab as a postdoc and resident chemist, and endows the lab with some long-anticipated chemistry expertise. After finishing his studies at the prestigous Lomonosov Moscow State University, Vitaly moved to Denmark to do his PhD at DTU – where he also went on to do a brief postdoc – before deciding to join our lab. Welcome on board, Vitaly, we´re very happy to have you around!

13 March 2015

Upcoming symposium

We are very proud to announce an – as we think – inspiring line up for the first ever Center for Biopharmaceuticals symposium on “Hot Topics in Chemical Biology” on Oct 6th 2015, find the flyer here. Attendance is free and only requires a simple registration email, so keep a free spot in your calendar for this exciting event!

 

2 March 2015

Big day for Tim

Sapere_aude_forskertalentTim got to mix and mingle among Danish Royalty and Ministers as he receives the coveted Sapere Aude DFF Research Talent award – congrats and well done! Find the link to the event here

22 February 2015

A good month

It´s been a very productive month, with lots of progress and exciting results on all ongoing projects – thanks for the hard work, everyone!

31 January 2015

A new toy

After variuos delays, missing equipment and a lots of fiddling with leaky chambers we now have our third e-phys rig up and running – a big thank you to Matthias and Nina. And to Karsten for putting up with all our special workshop requests!

31 January 2015

Talk in Aachen

IMG_2978_smallNo doubt, the hospital of Aachen, Germany has some of the most outrageous architecture imaginable. Not only does the outside look somewhat unique, architects really went to town on the inside, too, where they stuck almost exclusively to green floors, doors and walls – only interspersed by the odd silver wall or neon-colored door. Together, this provided a very unique backdrop to a very inspiring visit and many fruitful discussions with fellow ion channels aficionados that Stephan had the pleasure of meeting. Thank you, Stefan, for a great visit in Aachen!

13 January 2015

Say hi to Nina and Matthias

While Matthias embarks on his PhD, Nina will be joining us for her MSc – welcome to the lab! Oh, and their profiles will follow shortly!

16 December 2014

He did it again.

The good news just keep on coming for Tim, who was just awarded a Sapere Aude DFF Research Talent award – congratulations, what a great pre-Christmas gift! Read the full story here.

6 December 2014

A major milestone

GMO_small
Thanks to Janne’s efforts, we now have obtained GMO approval for our new lab lab space – a major milestone on our long and rocky road to being fully operational! To make things better, we were also finally able to provide Tim’s rig with a new home on the first floor. Thanks to everyone for their hard work – and for their patience!

4 December 2014

Good news

The lab receives a grant from the Novo Nordisk Foundation – we’re very honored and look forward to putting it to good use!

1 December 2014

Launch of ATPsignal.com

The newly launched ATPsignal website represents the web presence of this  interdisciplinary consortium of research groups that aims to unravel the enigmatic role of P2X7 receptors in human health and disease. Using highly complementary approaches ATPsignal will cover a broad range of P2X7 receptor biology, ranging from the atomic level to its role in organs and intact animals

15 November 2014

The wait is over

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After a long wait and numerous delays our new space is finally ready to move in! Thanks to everyone involved in the process of creating this great work space – and thanks to everyone in the lab for their patience and their help with the move!

14 November 2014

Talk in Santa Cruz

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Stephan had the pleasure of being invited to give a talk at the Universidad de La Laguna on Teneriffe. The island not only boasts breathtaking landscapes but also some of the finest ion channel labs around, making for a very worthwhile visit! Thanks for the invitation, Teresa!

3 November 2014

Ming joins the lab

Ming is a PhD student from the University of Queensland, Australia, who will be doing some work with unnatural amino acids in our lab for a couple of weeks – welcome in the lab!

28 September 2014

Congrats to Tim. Again.

Tim just secured a postdoctoral fellowship from the Lundbeck Foundation – someone is clearly on a roll these days. Stort tillykke, Tim!

28 September 2014

Talk at the caesar in Bonn

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The offices at this remarkable place must have one of the best views ever. No less impressive is the science done around there, making for a great visit – thanks for the invite, Thomas!

20 September 2014

Congrats to Tim!

Tim just secured himself a coveted postdoctoral fellowship from the DFF – a fantastic (and well-deserved) achievement! Check out the official DFF news release here

20 September 2014

SPS Meeting Sigtuna

IMG_2398Stephan had the pleasure to be invited to give a talk at the latest SPS meeting on Molecular Approaches to Membrane Transport in beautiful Sigtuna – a fun trip with lots of very interesting science!

18 August 2014

Open PhD position

We have available a PhD Fellowship in Ion Channel Electrophysiology starting December 2014  – click here to see the details

10 August 2014

Renovations under way

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Very exciting to see the mayhem on the first floor these days – the renovations of our new lab space are well under way and we should be able to move in before the end of the year!

4 July 2014

Lab summer outing

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Motivated by the beautiful summer weather we decided to take to the waters of the harbor for a little self-guided tour of the local attractions. Given we´re in Copenhagen it was only appropriate that we were powered by an über-environmentally friendly outboard engine delivering a whopping 12 V (from solar power-charged batteries, of course). We, on the other hand, were fueled by delicious smørrebrød and local brews, making for fun afternoon out on the water. We certainly hope to be able to make it a summer tradition!

27 June 2014

First recording

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After many delays we’re excited to report a first successful recording from a Xenopus laevis oocyte on our own rig. Better still, the second set up will be up and running as early as next week!

20 June 2014

Say hi to Federica

We´re very happy to announce the arrival of our first PhD student, Federica Gasparri! Originally from Milan, Federica just finished her MSc, which including an extended (and very successful) stay at Oxford Brooks. She has extensive experience with some of our favorite toys (think TEVC and the likes) and already an impressive publication record – check out her profile here!

17 June 2014

Seminar at CAU Kiel

Stephan had the pleasure of being invited to give a seminar as part of the ‘Physiological Colloquium’ series at the Christian-Albrechts-University Kiel

3 June 2014

First lab meeting with actual data!

Thanks to great efforts by Tim, Janne & Federica we just had our first lab meeting , including some first data from the lab! Thanks guys!

25 April 2014

First paper for the lab!

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A big thank you to our local expert in ligand-binding in Cys-loop receptors, Tim, for putting together this review for Frontiers in Physiology! Thanks to quite the deluge of research papers on related subjects he was on top of the literature and able to put together a comprehensive update of where the fields stands with regards to molecular recognition of agonists – nice work, Dr Lynagh! Find the manuscript here

25 April 2014

Seminar at KU Leuven

Stephan had the honor of being invited to beautiful Leuven for a seminar at KU Leuven

24 March 2014

Open PhD position

We have available a PhD Fellowship in Membrane Receptor Pharmacology, Structure & Function starting August 2014  – click here to see the details

23 March 2014

GRC Ligand Recognition and Molecular Gating

20140328_1561blue_croppedThe title is already quite the mouthful, but the conference keeps living up to it: a great mix of ion channelologists, transporter people and folks working on pumps mix and mingle for a week under the Californian sun. The highlights were some exciting posters on unatural amino acid incorporation and a few outstanding talks on new horizons in structural biology – looking forward to the 2016 edition (rumor has it the next one will be held in Spain)

 

11 March 2014

Janne joins the lab!

Janne Møgelhøj Colding has started as the labs laboratory technician. She has plenty of experience in both research and general lab management – and she is heading the resident Occupational Health & Safety committee. We could not have asked for a better fit and we´re very honored to have her around. Welcome Janne!

2 March 2014

Hot off the press

After we proudly announced being awarded a Lundbeck Foundation Fellowship, there recently were some media releases regarding the project associated with this fellowship, available both in Danish and in English.

21 February 2014

Biophysics Meeting 2014

SF_1aAttending the annual meeting of the Biophysical Society is always fun, even more so when San Francisco is the host city! Plenty of exciting science, meeting old and new friends and copious amounts of post-conference mix and mingle made for a good mix – looking forward to the 2015 edition (despite that one being hosted by Baltimore – in February)

6 February 2014

Congrats to Tim. Again.

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Propofol is an intravenous general anesthetic that has recently garnered much attention, not least due to its alleged involvement in the death of a certain King of Pop. Tim now shows how this innocent looking compound can both inhibit and enhance currents through some ligand-gated ion channels – doing so via a single site! See the whole story published as a prestigious Brief Communication in The Journal of Neuroscience.

4 February 2014

Congrats to Tim

Tim has been invited as a speaker at the ‘Anthelmintics: From Discorvery to Resistance’ Meeting in San Francisco – congrats!

16 January 2014

Tim Lynagh joins the lab

Tim Lynagh is the first post doc to join the lab! After finishing his PhD in Australia, the Bundaberg native moved to Germany for his first post doc, before deciding on his move to Copenhagen – welcome Tim, great to have you on board!

10 December 2013

Carlsberg Foundation Grant

More good news for the lab, as we just received an equipment grant from the Carlsberg Foundation!

1 November 2013

Lundbeck Foundation Fellowship

The lab is very honored to announce a major grant from the Lundbeck Foundation in form of a Lundbeck Foundation Fellowship to Stephan Pless. Check out the video for some glossy info on the project.

22 September 2013

Getting closer

The floor plans are ready and the renovations of the lab space are about to start – very exciting times for the lab and its host, the Centre for Biopharmaceuticals.