Biophysics 2020 was the last in-person meeting pre-Covid, so it was only fitting that Biophysics 2022 would kick off real-life conferences again. Although only Debayan and Stephan made it to California in the end, the lab was strongly represented with 2 talks and 3 posters. Definitely exciting to catch up with friends and collaborators in person again – and big thanks to the organisers for an outstanding and diverse program, as well as for providing a safe environment.