Our latest endeavour into protein semi-synthesis / MD combo is out on bioRxiv. Together with our fantastic collaborators from the Lucie Delemotte lab, we show how Nav1.5 patient mutations can be functionally benign – until they get phosphorylated and then wreak havoc on inactivation. Great job by Iacopo and Hendrik putting this together and we are grateful for support by DFF and the Lundbeck Foundation.