Led by former postdoc Chow (now group leader in Sydney), the work was just published in PNAS. The study was started by former MSc student Katharina, and later expanded by contributions from Sam and our collaborators in the Carnevale lab. It outlines that the lateral fenestrations do indeed block access to a hidden drug binding site with the NALCNÂ pore module and reveals a potentially promising pharmacophore to pharmacologically target NALCN in the future. Congrats to everyone involved!
