Congrats to Tim, Jose and Camilla for getting their work on ibuprofen and ASICs published in J Med Chem. They investigated the ibuprofen/ASIC interaction by deciphering the mechanism of inhibition, identifying the ibuprofen binding site and using a series of ibuprofen analogs to performing structure-activity-relationships. The KU press release can be found HERE, whereas the full paper can be accessed HERE.
