We are very grateful for an infrastructure grant from the Carlsberg Foundation that will support our efforts to decipher the function and structure of the NALCN channelosome.

After what felt like an eternity, Stephan got to talk in person again abroad – big thanks to Lucie Delemotte and Reba Howard for hosting a fun visit at the SciLife Labs in Stockholm!

Today, we welcome Paolo Zucculini from Italy, who will do a short stay in our lab to get some experience in VCF recordings.

Congrats to Stephanie for this epic effort to assemble an overview of what animal models have taught us about the potential of acid-sensing ion channels as therapeutic targets. Apart from the well-studied stroke implications and the tricky area of pain, ASICs may turn out to be suitable targets in a number of other diseases – check out the details here.

After many years of big efforts, Nina’s paper on incorporation of photo-crosslinking ncAAs is finally out in PLoS Biology. The project took many twists and turns, but thanks to the courage and tenacity of Nina, it all worked out in the end. Special kudos to Jacob Andersen for kicking off the idea and big thanks to our fantastic collaborators from the Andrea Sinz group and Nanion!

Today, we welcome four new people to the group: Caroline is joining as a scholar student to work on ASICs with Stephanie; Gül and Sofie will be working on ASICs with Debayan as part of their MSc thesis and Sam joins from Oxford as a postdoc to work on NALCN. Welcome and we look forward to having you around!

The CBP came with 4 teams to the 2021 edition of the DHL relay. Big thanks to Hendrik and Daniela for organising this fun event in the park

This year’s CBP retreat was all about creativity (day 1) and equality, diversity and inclusion (day 2). Set at the beautiful F’berg campus, we were lucky to be entertained by excellent speakers: Itai Yanai (NYU) and Martin Lercher (Düsseldorf) from the Night Science podcast & Roshni Mooneeram (EMBL) and Vanessa Hall (UCPH). Big thanks to everyone involved for making this happen!

We packed our bags and headed to Skagen for three days of fun in the sun. Big thanks to the organising postdocs!

Big congratulations to Zeshan for his heroic effort on deciphering how M1 and pre-M1 contribute to ion selectivity in ASICs and ENaCs. Him, Matthias and Tim were fortunate enough to be assisted by strong collaborators from both academia (Mike Althaus, Bonn) and industry (Nanion Technologies, Germany), but it was Zeshan who really spear-headed this project. It ended up involving chimeras, non-canonical amino acids, automated and single channel patch-clamp and much more and really helped us understand key differences between ASICs and their constitutively active cousins from the ENaCs family. The paper just came out in JGP.