Archives

Feng is off to the UK

Feng will work at the University of Cambridge until January 2024 as his stay abroad – have a great time over there and best of luck with your project!

Updated preprint

The updated preprint on our protein engineering efforts with ASIC1a is now on bioRxiv. Thanks to the efforts by Stephanie Heusser and Joe Harrison (Univ of the Pacific, US) we have added new functional and computational data on how non-canonical Lys211 analogs disrupt chloride binding and channel function. Big thanks to the entire team for their  resubmission efforts – and to our funding sources Lundbeck Foundation and DFF.

Welcome (back), Nadine

After an internship in 2022, we are delighted to welcome Nadine Ritter back to the lab! She just completed a productive PhD project and joins the lab with a MSCA postdoctoral fellowship to work on NALCN – welcome back, we’re looking forward to having you around!

Mette speaks at GRC

Mette had the honour of being invited to present her latest efforts on an channel-transporter interaction at the Mechanisms of Membrane Transport GRC in Switzerland – congrats!

Congrats to Victor

Congratulations to Victor for successfully defending his MSc work! He used – under the supervision of Sam Usher and Alex Hauser – a variety of bioinformatics approaches to study NALCN and we look forward to testing some of his predictions. Special thanks to his supervisors for their efforts with this project!

Finally.

After a long break, we finally resumed the lab tradition of taking advantage of the summer weather to cruise around the harbour, followed by a BBQ – and some impromptu table tennis.

A trip down memory lane

Exactly 21 years after a summer internship in the laboratory of Prof Ursula Jakob, Stephan returns to the University of Michigan to present some of our latest NALCN and ASIC work. Big thanks to Dave Jones for organising a fantastic visit!

Caroline defends her MSc thesis

Congratulations to MSc student Caroline for successfully defending her thesis work! It was an absolute pleasure to have you around, we’re grateful for all the progress on the project and wish you all the best for the future Special thanks to Stephanie for fantastic supervision.

New DFF grants

We are very grateful to have received funding from DFF for our ongoing efforts with NALCN, as well as ASIC. The latter grant is a collaboration with the labs of Henriette Autzen and Joe Rogers and we hugely look forward to getting this off the ground together with them. Watch this space for updates on the projects.

Lab members on the road

Our TEVC rigs are less busy than usual these days because Hendrik and Sam are busy patching neurons abroad. Specifically they are visiting the labs of Arnaud Monteil in Montpellier and Christian Rosenmund in Berlin, respectively. Happy recordings and we look forward to welcoming you back later in the year!