Huge congrats to the whole team, lead by the terrific and fearless duo of Keith and Iacopo, for putting together a terrific study on protein engineering! Initially not more than a somewhat abstruse idea, the team managed to insert synthetic peptides into a variety of proteins in life cells using what has become internally known as ‘intein magic’. The work is now published at Nature Communications, including a blog post in the Nature Research Bioengineering Community.
Thanks also to our collaborators from the TampĂ© group in Frankfurt – and to our funders for enabling us to bring this idea to life.