The updated preprint on our protein engineering efforts with ASIC1a is now on bioRxiv. Thanks to the efforts by Stephanie Heusser and Joe Harrison (Univ of the Pacific, US) we have added new functional and computational data on how non-canonical Lys211 analogs disrupt chloride binding and channel function. Big thanks to the entire team for their resubmission efforts – and to our funding sources Lundbeck Foundation and DFF.
